2017-09-16 16:54:232025-05-24 03:13:36
description
DNA polymerase III (alpha subunit), part of the replisome
DNA polymerase III, leading strand polymerase (alpha subunit), part of the [SW|replisome]
locus
BSU16580
BSU_16580
function
DNA replication
[[category|DNA replication]]
outlinks
bsu
BSU16580
BSU_16580
The protein
Catalyzed reaction/ biological activity
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1) (according to Swiss-Prot)
required for bacteriophage SPP1 replication [Pubmed|23268446]
2'-deoxyribonucleoside 5'-triphosphate + DNA(n) --> diphosphate + DNA(n+1) (according to UniProt)
required for bacteriophage SPP1 replication [Pubmed|23268446]
The protein
Protein family
PolC subfamily (according to Swiss-Prot)
DNA polymerase type-C family (with [[protein|YorL]] and [[protein|DnaE]], according to UniProt)
The protein
[SW|Localization]
forms foci [Pubmed|21958350]
cytoplasm (according to Swiss-Prot)
forms foci [Pubmed|21958350]
about three molecules of PolC at each replication fork [pubmed|28002733]
References
Reviews
References
Original publications
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
[SW|Exonuclease domain] (aa 421-578) (according to UniProt)
Expression and Regulation
additional information
about 60 molecules per cell [pubmed|28002733]